Native thrombin from human plasma, bound to agarose beads. Thrombin is a key enzyme in the coagulation cascade. Converts fibrinogen to fibrin and activates factor XIII, which cross-links and stabilizes the fibrin polymer.

In 100 mM NaCl, 20 mM Tris-HCl, ≤0.1% sodium azide, pH 7.4.

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Xiang, B., et al. 1998. Proc. Natl. Acad. Sci. USA95, 7412.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Toxicity: Standard Handling (A)