assay
≥97% (SDS-PAGE)
Quality Level
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤1 EU/μg Endotoxin (EU/μg TGF-β1)
shipped in
ambient
storage temp.
−20°C
General description
CHO细胞中表达的重组人转化生长因子β1。可促进静息的人B淋巴细胞、神经胶质瘤细胞和三叉神经鞘瘤细胞的凋亡。在各种疾病中诱导细胞外基质积聚。
Biochem/physiol Actions
ED₅₀ = 0.04-0.1 ng/ml
Physical form
由含50 µg BSA/µg TGF-β1、35％乙腈、0.1％TFA的无菌滤过溶液冻干。
Preparation Note
溶解后，分装并冷冻保存（-20°C）。避免溶液反复冻融。储备溶液在-20°C下可稳定保存至多3个月。
用含有≥0.1％ HSA或BSA的4 mM无菌HCl复溶成浓度≥1 µg/m的溶液。
Other Notes
Shibuya, H., et al. 1996.Science272, 1179.
Bottlinger, E.P., et al. 1995.Proc.Natl.Acad.Sci. USA93, 5877.
Lomo, J., et al. 1995.J. Immunol.154, 1634.
Marushige, K., and Marushige, Y. 1995.Anticancer Res.14, 2419.
Yamazaki, M., et al. 1994.Am. J. Pathol.144, 221.
Bottlinger, E.P., et al. 1995.Proc.Natl.Acad.Sci. USA93, 5877.
Lomo, J., et al. 1995.J. Immunol.154, 1634.
Marushige, K., and Marushige, Y. 1995.Anticancer Res.14, 2419.
Yamazaki, M., et al. 1994.Am. J. Pathol.144, 221.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：标准处理（A）
存储类别
11 - Combustible Solids
wgk
WGK 3
Holly B Hindman et al.
Investigative ophthalmology & visual science, 51(4), 1935-1942 (2009-11-13)
Purpose. To characterize phenotypic differences between anterior and posterior corneal keratocytes after stimulation with the profibrotic agent transforming growth factor-beta1 (TGF-beta1) in vitro. Methods. Sixteen corneas from healthy felines were obtained immediately after death. Lamellar dissection was performed to separate
Hon Wai Koon et al.
The American journal of pathology, 177(5), 2300-2309 (2010-10-05)
Substance P (SP) and the neurokinin-1 receptor (NK-1R) are involved in the development of colitis and mucosal healing after colonic inflammation. We studied whether SP modulates colonic fibrosis by using a chronic model of trinitrobenzenesulfonic acid (TNBS)-induced colitis in wild-type
Nagat Frara et al.
Connective tissue research, 59(1), 30-44 (2017-04-13)
Transforming growth factor beta 1 (TGFbeta-1) and connective tissue growth factor (CCN2) are important mediators of tissue repair and fibrosis, with CCN2 functioning as a downstream mediator of TGFβ-1. Substance P (SP) is also linked to collagen production in tenocytes.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 8070419025 | 04022536884615 |
| 8070410250 | 04022536393148 |
| 8070410005 | 04022536393131 |
| 8070411000 | 04022536393155 |
| Y0000659 | 04061833804414 |
| P74370-20KG | 04061838124562 |
| P74370-25G | 04061838100627 |
| W482900-100G | 04061837542077 |
| W482900-500G | 04061837542091 |
| 240338-50G | 04061838590367 |
| 83300-250ML | 04061833005545 |
| P74370-18KG | 04061829452452 |
| P74370-1KG | 04061834394761 |
| P74370-500G | 04061834394778 |
| 83300-1L | 04061833005538 |
| 616455-2UG | 04055977185874 |