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COA分析证书/COQ

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625625

Trehalose, Dihydrate

Name: Trehalose, Dihydrate
Brand: MM

Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.

别名:

Trehalose, Dihydrate, 1-O-α-D-Glucopyranosyl-α-D-glucopyranoside

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About This Item

经验公式（希尔记法）:

C₁₂H₂₂O₁₁ · 2H₂O

CAS Number:

6138-23-4

分子量:

378.33

MDL编号:

MFCD00071594

UNSPSC代码:

12352201

NACRES:

NA.79

描述

Merck USA index - 14, 9580

质量水平

100

方案

≥97.5% (by Assay)

表单

solid

制造商/商品名称

Calbiochem^®

储存条件

OK to freeze

溶解性

water: 100 mg/mL

痕量阳离子

Fe: <5 ppm
heavy metals: <10 ppm

运输

ambient

储存温度

15-25°C

SMILES字符串

O1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO.O.O

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

一般描述

Non-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.

Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.

警告

Toxicity: Standard Handling (A)

其他说明

Sarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med.10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)