627624
D-Val-Phe-Lys氯甲基酮，二氢氯化物
Selective irreversible inhibitor of plasmin with high selectivity for plasmin (IC50 = 100 pM for human plasmin) over urokinase.
别名:
纤溶酶抑制剂，2HCl
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选择尺寸
关于此项目
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥90% (HPLC)
Form:
lyophilized solid
Quality level:
Storage condition:
OK to freeze, desiccated
assay
≥90% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
off-white
solubility
DMSO: 5 mg/mL
shipped in
ambient
Quality Level
storage temp.
2-8°C
相关类别
General description
选择性不可逆的纤溶酶抑制剂，对纤溶酶（人纤溶酶的 IC50 = 100 pM）的选择性高于尿激酶。
Biochem/physiol Actions
主靶
人纤溶酶
人纤溶酶
产物不与ATP竞争。
可逆：否
细胞可渗透性：否
靶标IC50：对于人纤溶酶为100 pM
Packaging
用惰性气体包装
Preparation Note
复溶后，等分并冷冻保存（-20°C）。贮备溶液在-20°C下可稳定保存至多1个月。
来自目录：
说明字段-添加“（对于人纤溶酶₅₀ = 100 pM）”
来自目录：
说明字段-添加“（对于人纤溶酶₅₀ = 100 pM）”
Other Notes
H-D-Val-Phe-Lys-CMK
Woessner, J.F., Jr., et al. 1989.Steroids54, 491.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：标准处理（A）
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Hasam Madarati et al.
Scientific reports, 14(1), 9073-9073 (2024-04-21)
ADAMTS13, a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13, regulates the length of Von Willebrand factor (VWF) multimers and their platelet-binding activity. ADAMTS13 is constitutively secreted as an active protease and is not inhibited by circulating
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