648311
Tris碱
≥99% dry basis (titration), crystalline solid, pH 10.3-11.3, Ultrol® Grade
别名:
三（羟甲基）氨基甲烷, 2-氨基-2-(羟甲基)-1,3-丙二醇, THAM, Tris 碱, 氨基丁三醇
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关于此项目
线性分子式:
NH2C(CH2OH)3
化学文摘社编号:
分子量:
121.14
UNSPSC Code:
12161705
NACRES:
NA.25
MDL number:
Beilstein/REAXYS Number:
741883
产品名称
Tris碱, ULTROL® Grade, ≥99% dry basis (titration), useful in pH range 10.3-11.3
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
SMILES string
NC(CO)(CO)CO
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
description
Merck USA index - 14, 9772
assay
≥99% dry basis (titration)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
useful pH range
7-9
pKa (25 °C)
8.1
bp
219-220 °C/10 mmHg (lit.)
mp
167-172 °C (lit.)
solubility
water: 1 M
cation traces
heavy metals: ≤5 ppm
shipped in
ambient
storage temp.
10-30°C
Quality Level
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Application
- Development of an Antigen Capture Lateral Flow Immunoassay for the Detection of Burkholderia pseudomallei.: 本研究使用 Tris 碱开发用于检测伯克霍尔德菌的侧向层析免疫测定法，增强临床微生物学的诊断能力 (Nualnoi et al., 2024)。
Disclaimer
毒性：刺激性（B）
General description
吸光度(1.0 M, H2O, 260 nm)：<0.05.
在10.3-11.3的pH范围内有效。25°C时PKa为8.1。
已广泛用作生物缓冲液（吸光度：<0.05，在260 nm，1.0 M，H2O）。1.0 M H2O溶液的pH值范围为10.3-11.3，在20°C时pKa为8.3。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Aura E Ionescu et al.
International journal of molecular sciences, 20(24) (2019-12-19)
Eyes absent (EYA) are non-thiol-based protein tyrosine phosphatases (PTPs) that also have transcriptional co-activator functions. Their PTP activity is involved in various pathologies. Recently, we demonstrated that Src tyrosine kinase phosphorylates human EYA3 by controlling its subcellular localization. We also
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