648468
Triton™ X-114 Solution
10% in H₂O, PROTEIN GRADE®
别名:
(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol solution, t-Octylphenoxypolyethoxyethanol; Polyethylene glycol tert-octylphenyl ether
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关于此项目
化学文摘社编号:
NACRES:
NA.21
UNSPSC Code:
12161902
MDL number:
Beilstein/REAXYS Number:
2315025
产品名称
(1,1,3,3-四甲基丁基)苯基-聚乙二醇 溶液, Non-ionic detergent and emulsifier. HLB 12.4. Cloud point 22°C.
InChI key
HNLXNOZHXNSSPN-UHFFFAOYSA-N
InChI
1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3
SMILES string
CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1
description
RTECS - MD0907600
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<200 μM Aldehyde
<200 μM peroxide
color
clear
conductivity
<50 μmho
CMC
350 μM
shipped in
ambient
storage temp.
2-8°C
Quality Level
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Application
- Determination of nine aromatic amines in water by cloud point extraction-gas chromatography-mass spectrometry.: This study utilized Triton X-114 for cloud point extraction to enhance the detection sensitivity of aromatic amines in water samples. The detergent played a crucial role in the efficient extraction and subsequent analysis of these compounds, highlighting its utility in environmental monitoring and analytical chemistry (Yang et al., 2024).
- An innovative lab-scale production for a novel therapeutic DNA vaccine candidate against rheumatoid arthritis.: Triton X-114 was employed in the purification steps to ensure the integrity and activity of the vaccine components. This detergent′s role in protein solubilization and membrane protein isolation was pivotal in the development of the therapeutic candidate, demonstrating its importance in biotechnological applications (Long et al., 2024).
- Lipoprotein signal peptidase-deficient Streptococcus pneumoniae exhibits impaired Toll-like receptor 2-stimulatory activity.: The study used Triton X-114 for the extraction and analysis of membrane proteins, which facilitated the investigation of bacterial interactions with host immune receptors. This application underscores the detergent′s effectiveness in microbial research and immunology (Domon et al., 2024).
- Improvement in the Chromium(VI)-Diphenylcarbazide Determination Using Cloud Point Microextraction; Speciation of Chromium at Low Levels in Water Samples.: Triton X-114 was used for cloud point extraction to improve the sensitivity and accuracy of chromium speciation in water samples. This method highlights the detergent′s role in environmental analytical chemistry, enhancing the detection of trace metal species (Mouco-Novegil et al., 2023).
Disclaimer
Toxicity: Irritant (B)
General description
HLB 12.4. Cloud point 22°C.
Non–ionic detergent and emulsifier.
Non-ionic detergent and emulsifier (cloud point: 22°C; CMC: 350 µM; HLB: 12.4).
Other Notes
D’Arrigo, A., et al. 1993. J. Biol. Chem.268, 2802.
Packaging
Packaged under inert gas
Physical form
A 10% aqueous solution.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
PROTEIN GRADE is a registered trademark of Merck KGaA, Darmstadt, Germany
Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Celine Brooks et al.
Frontiers in molecular neuroscience, 11, 16-16 (2018-02-08)
Primary cilia are microtubule-based organelles, which protrude from the plasma membrane and receive a wide range of extracellular signals. Various cilia use G protein-coupled receptors (GPCRs) for the detection of these signals. For instance, vertebrate rod photoreceptors use their cilia
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