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Merck
CN

648480

Sigma-Aldrich

Troponin I, Human Heart

别名:

Troponin I, Human Heart, hcTnI

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化学文摘社编号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.32
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方案

≥95% (SDS-PAGE)

质量水平

表单

lyophilized

制造商/商品名称

Calbiochem®

储存条件

OK to freeze

溶解性

urea/Tris buffer (0.02 M Tris, HCl, pH 7.5, 7 M urea, 5 mM EDTA, 15 mM 2-mercaptoethanol): 1 mg/mL

运输

ambient

储存温度

−20°C

一般描述

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca2+, thus inhibiting the ATPase activity of actomyosin. Presence of hcTnI in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for antisera production. Also useful as a tracer for iodination.

外形

Lyophilized from 10 mM HCl.

制备说明

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

其他说明

Falahati, A., et al. 1999. Am. Heart J. 137, 332.
Mangano, D.T. 1994. Anesthesiology 81, 1317.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Toxicity: Standard Handling (A)

法规信息

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Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

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