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Merck
CN

662045

Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb

liquid, Calbiochem®

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human, rat, mouse
Application:
Citations:
17
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biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity

human, rat, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Immunoblotting (1:1000))

isotype

IgG

shipped in

wet ice

storage temp.

−70°C

target post-translational modification

unmodified

Gene Information

human ... UCP1(7350)

General description

Protein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
Recognizes the UCP-1 protein.
This Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb is validated for use in Immunoblotting for the detection of Uncoupling Protein-1 (UCP-1) (145-159).

Immunogen

Mouse
a synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1

Application

Immunoblotting (1:1000)

Physical form

In PBS.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Does not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Traci A Czyzyk et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(4), 1151-1159 (2009-11-18)
General opioid receptor antagonists reduce food intake and body weight in rodents, but the contributions of specific receptor subtypes are unknown. We examined whether genetic deletion of the kappa-opioid receptor (KOR) in mice alters metabolic physiology. KOR-knockout (KO) and wild-type
Traci A Czyzyk et al.
American journal of physiology. Endocrinology and metabolism, 305(2), E282-E292 (2013-05-30)
Obesity continues to be a global health problem, and thus it is imperative that new pathways regulating energy balance be identified. Recently, it was reported: (Hayashi K, Cao T, Passmore H, Jourdan-Le Saux C, Fogelgren B, Khan S, Hornstra I
C L Plaisier et al.
Nutrition & diabetes, 2, e46-e46 (2013-03-01)
A better understanding of the processes influencing energy expenditure could provide new therapeutic strategies for reducing obesity. As the metabolic activity of the brown adipose tissue (BAT) and skeletal muscle is an important determinant of overall energy expenditure and adiposity



全球贸易项目编号

货号GTIN
662045-100UL04055977261073