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676493

VEGF Inhibitor, Flt₂₋₁₁

Name: VEGF Inhibitor, Flt<SUB>2</SUB>₋<SUB>11</SUB>
Brand: MM

The VEGF Inhibitor, Flt2-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

别名:

VEGF Inhibitor, Flt₂₋₁₁, NITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I

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关于此项目

经验公式（希尔记法）:

C₆₁H₁₀₄N₁₄O₁₅

分子量:

1273.56

NACRES:

NA.77

UNSPSC Code:

12352200

Assay:

≥95% (HPLC)

Form:

lyophilized solid

Quality level:

100

Storage condition:

OK to freeze, desiccated (hygroscopic)

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属性

Quality Level

100

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

acetonitrile: 20%, DMSO: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

说明

General description

An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is shown to inhibit angiogenesis in chick chorioallantoic membrane and inhibits VEGF-induced vascular permeability. Neither binds to vascular endothelial growth factor (VEGF) nor inhibits its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.

Biochem/physiol Actions

Cell permeable: no

Primary Target
VEGF

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Other Notes

H-Asn-Ile-Thr-Val-Thr-Leu-Lys-Lys-Phe-Pro-Leu-OH

Tan, D.C., et al. 2001. FEBS Lett.494, 150.

Legal Information

Sold under license of U.S. Patent 6,200,954.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c