677175-M
Vinblastine Sulfate
Antitumor alkaloid drug.
别名:
Vinblastine Sulfate
选择尺寸
关于此项目
SMILES string
[S](=O)(=O)(O)O.N21C[C@H](C[C@@](C2)(O)CC)C[C@@](c8[nH]c9c(c8CC1)cccc9)(c3cc4c(cc3OC)N([C@@H]5[C@]64[C@H]7N(CC6)CC=C[C@]7([C@H]([C@]5(O)C(=O)OC)OC(=O)C)CC)C)C(=O)OC
InChI
1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)/t28-,37+,38-,39-,42+,43-,44-,45+,46+;/m1./s1
InChI key
KDQAABAKXDWYSZ-JKDPCDLQSA-N
description
Merck USA index - 14, 9982
assay
≥98% (HPLC)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
color
white
solubility
water: 50 mg/mL
Quality Level
General description
Biochem/physiol Actions
Interaction of tubulin with microtubule-associated proteins, specifically Tau and MAP2
Preparation Note
Other Notes
Boscoboinik, D., et al. 1994. Biochem. Biophys. Res. Commun.199, 374.
Smith, C.D., et al. 1994. Cancer Lett.79, 213.
Smith, C.D., et al. 1994. Cancer Res.54, 3779.
Tsukidate, K., et al. 1993. Am. J. Pathol. 143, 198.
Jagetia, G.C., and Jacob, P.S. 1992. Mutat. Res.280, 87.
Jordan, M.A., et al. 1992. J. Cell Sci. 102, 401.
Prasad, V., et al. 1992. J. Protein Chem.11, 509.
Legal Information
Disclaimer
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Muta. 2 - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
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