8.18586
Isophorone diisocyanate
(mixture of cis- and trans-isomers) for synthesis
别名:
Isophorone diisocyanate, 5-Isocyanato-1-isocyanatomethyl-1,3,3-trimethylcyclohexane, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
选择规格
关于此项目
vapor pressure
0.0004 hPa ( 20 °C)
Quality Segment
assay
≥99.0% (GC)
form
liquid
autoignition temp.
430 °C
potency
4825 mg/kg LD50, oral (Rat), >7000 mg/kg LD50, skin (Rat)
expl. lim.
0.7-4.5 % (v/v)
bp
158-159 °C/13 hPa
mp
-60 °C
transition temp
flash point 155 °C
solubility
0.015 g/L (slow decomposition)
density
1.06 g/cm3 at 20 °C
storage temp.
2-30°C
SMILES string
N(=C=O)C1CC(CC(C1)(C)C)(CN=C=O)C
InChI
1S/C12H18N2O2/c1-11(2)4-10(14-9-16)5-12(3,6-11)7-13-8-15/h10H,4-7H2,1-3H3
InChI key
NIMLQBUJDJZYEJ-UHFFFAOYSA-N
Application
- Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery.: This study explores the development of thermoresponsive random poly(ether urethanes) synthesized using Isophorone diisocyanate. These polymers exhibit adjustable lower critical solution temperatures (LCSTs), making them suitable for controlled anticancer drug delivery applications. The research highlights the potential of Isophorone diisocyanate in creating advanced materials for medical use, specifically in drug delivery systems (Sardon et al., 2015).
Analysis Note
Density (d 20 °C/ 4 °C): 1.060 - 1.062
Identity (IR): passes test
警示词
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Aquatic Chronic 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
怎么回事？
WGK 2
闪点 (F)
325.4 °F - closed cup
闪点 (°C)
163 °C - closed cup
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials