8.52375
Fmoc-hLys(Boc)-OH
Novabiochem®
别名:
Fmoc-hLys(Boc)-OH, N-α-Fmoc-N-ω-t.-Boc-L-homolysine
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关于此项目
经验公式（希尔记法）:
C27H34N2O6
化学文摘社编号:
分子量:
482.57
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
SMILES string
N([C@@H](CCCCCNC(=O)OC(C)(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C27H34N2O6/c1-27(2,3)35-25(32)28-16-10-4-5-15-23(24(30)31)29-26(33)34-17-22-20-13-8-6-11-18(20)19-12-7-9-14-21(19)22/h6-9,11-14,22-23H,4-5,10,15-17H2,1-3H3,(H,28,32)(H,29,33)(H,30,31)/t23-/m0/s1
InChI key
CLFMIWUWBOOJLY-QHCPKHFHSA-N
product line
Novabiochem®
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
Quality Level
General description
This homolog of lysine has been used to modulate ion-pairing interactions between Lys and enzyme carboxylate groups in SAR studies [1].
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. J. Kennedy, et al. (1997) Bioorg. Med. Chem. Lett., 7, 1937.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. J. Kennedy, et al. (1997) Bioorg. Med. Chem. Lett., 7, 1937.
Application
Fmoc-hLys(Boc)-OH can be used as a building block in the solid phase peptide synthesis.
Analysis Note
Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Probing the flexibility of the catalytic nucleophile in the lyase catalytic pocket of human DNA polymerase β with unnatural lysine analogues
Daskalova SM, et al.
Biochemistry, 56(3), 500-513 (2017)
Exploring the impact of the side-chain length on peptide/RNA binding events
Sbicca L, et al.
Physical Chemistry Chemical Physics, 19(28), 18452-18460 (2017)
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