产品名称
Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A, serum, Chemicon®
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
species reactivity (predicted by homology)
rat
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Analysis Note
Routinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.
Application
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Toxicology & Drug Resistance
Toxicology & Drug Resistance
Western Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
141 kDa
This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.
Immunogen
Epitope: AA N629 – W704
Recombinant
Physical form
Raw rabbit serum with 0.05% sodium azide.
Preparation Note
Maintain at -20°C for up to 12 months from date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Adám Sike et al.
PloS one, 9(1), e84915-e84915 (2014-01-11)
The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious problems in cancer treatment. With the aim to uncover whether changes induced by epigenetic mechanisms in the expression level
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