AB10418
Anti-Puma BH3 domain Antibody
from rabbit
别名:
BCL2 binding component 3, Bcl-2 binding component 3, p53 up-regulated modulator of apoptosis
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Bbc3(170770)
一般描述
21 kDa
PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis
免疫原
This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma.
应用
Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB.
生化/生理作用
Other species have not been tested.
The antibody reacts with the 21 kDa Puma BH3 domain protein.
外形
Format: Purified
分析说明
Control
Western Blot : Mouse brain lysate
Western Blot : Mouse brain lysate
Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Bhargab Kalita et al.
PloS one, 11(12), e0168525-e0168525 (2016-12-31)
Development of an effective radio protector to minimise radiation-inflicted damages have largely failed owing to inherent toxicity of most of the agents examined so far. This study is centred towards delivering protection to lethally irradiated mice by pre-administration of a
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