AB10418
Anti-Puma BH3 domain Antibody
from rabbit
别名:
BCL2 binding component 3, Bcl-2 binding component 3, p53 up-regulated modulator of apoptosis
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
mouse
Citations:
1
Technique(s):
western blot: suitable
Uniprot accession no.:
产品名称
Anti-Puma BH3 domain Antibody, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Bbc3(170770)
Analysis Note
Control
Western Blot : Mouse brain lysate
Western Blot : Mouse brain lysate
Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate.
Application
Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB.
Biochem/physiol Actions
Other species have not been tested.
The antibody reacts with the 21 kDa Puma BH3 domain protein.
General description
21 kDa
PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis
Immunogen
This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Bhargab Kalita et al.
PloS one, 11(12), e0168525-e0168525 (2016-12-31)
Development of an effective radio protector to minimise radiation-inflicted damages have largely failed owing to inherent toxicity of most of the agents examined so far. This study is centred towards delivering protection to lethally irradiated mice by pre-administration of a
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