biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, rat, human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... KLK3(354)
General description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.
~31 kDa observed.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.
Application
This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).
Biochem/physiol Actions
Other species have not been tested.
The antibody reacts with the 29 kDa KLK3 antigen.
Physical form
Format: Purified
Saturated Ammonium Sulfate (SAS)
Preparation Note
Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°
Analysis Note
Control
Western Blot : Mouse brain lysate.
Western Blot : Mouse brain lysate.
Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Ana M Blázquez-Medela et al.
Medicine, 94(41), e1617-e1617 (2015-10-16)
Early detection of hypertensive end-organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients suffering from arterial hypertension. Presently, there are no biomarkers for the detection of hypertensive target organ damage, most outstandingly including blood vessels, the
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