AB10516

抗血管生成素-1抗体

Name: 抗血管生成素-1抗体
Brand: MM

from rabbit

别名:

Hepatic fibrinogen/angiopoietin-related protein, PPARG angiopoietin related protein, angiopoietin-like 4, angiopoietin-like 4 protein, angiopoietin-related protein 4, fasting-induced adipose factor, hepatic angiopoietin-related protein, peroxisome prolif

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

western blot

Species reactivity:

horse (95% sequence homology), dog (95% sequence homology), mouse (100% sequence homology), rat (95% sequence homology), bovine (95% sequence homology), mouse, human (90% sequence homology), pig (95% sequence homology)

Citations:

Technique(s):

western blot: suitable

Uniprot accession no.:

O08538

主要文件

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产品名称

抗血管生成素-1抗体, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

technique(s)

western blot: suitable

NCBI accession no.

NM_001146.3

UniProt accession no.

O08538

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ANGPT1(284)

Analysis Note

对照
小鼠肾裂解液

通过蛋白质印迹在小鼠肾裂解液中进行了评估。
蛋白质印迹分析：：该批次的1：1,000稀释液在10 µg小鼠肾裂解液中检测到血管生成素-1。

Application

抗血管生成素-1抗体是针对血管生成素-1的抗体，可用于WB。

Biochem/physiol Actions

该抗体可识别血管生成素-1。

General description

57 kDa

哺乳动物原始脉管系统的重塑以形成成熟的心血管系统包括许多指导内皮细胞发育的因素。血管生成素-1是一种与内皮特异性Tie-2受体相互作用的血管生成分泌型蛋白。它主要在发育中的内皮细胞中表达。在胚胎发育过程中，Ang-1结合并诱导Tie-2的酪氨酸磷酸化。Ang-1似乎在介导基质和间充质中起关键作用。它介导血管成熟和稳定。Ang-1可能在心脏发育中起关键作用。Ang-1缺陷小鼠模仿Tie-2缺陷动物表现出的表型。Ang-1的同系物，称为血管生成素-2，可以作为Ang-1和Tie-2的拮抗剂。Ang-1和Ang-2具有约60%的序列同源性。

Immunogen

该抗体是从用选自小鼠血管生成素-1的KLH偶联合成肽免疫的兔中产生的。

Other Notes

浓度：请参考批次特异性浓缩物的检验报告。

Physical form

形式：纯化

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

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Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes.

Feng, et al.

Frontiers in Cellular Neuroscience, 17, 1125412-1125412 (2023)

An MRI Study of Neurovascular Restorative After Combination Treatment With Xiaoshuan Enteric-Coated Capsule and Enriched Environment in Rats After Stroke.

Yu Zhan et al.

Frontiers in neuroscience, 13, 701-701 (2019-07-30)

Xiaoshuan enteric-coated capsule (XSEC) is a Chinese medicinal compound widely used for treatment of ischemic cerebrovascular diseases. Enriched environment (EE) is an effective rehabilitative protocol designed to enhance sensorimotor, cognitive and social stimulation. This study aimed to apply magnetic resonance

Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs.

Mansoor Syed et al.

Nature communications, 8(1), 1173-1173 (2017-10-29)

Hyperoxia-induced acute lung injury (HALI) is a key contributor to the pathogenesis of bronchopulmonary dysplasia (BPD) in neonates, for which no specific preventive or therapeutic agent is available. Here we show that lung micro-RNA (miR)-34a levels are significantly increased in

Integrin α5β1-Ang1/Tie2 receptor cross-talk regulates brain endothelial cell responses following cerebral ischemia.

Defang Pang et al.

Experimental & molecular medicine, 50(9), 117-117 (2018-09-07)

We have previously demonstrated that in response to cerebral ischemia (CI), the growth factor angiopoietin-1 (Ang1) and α5β1 integrin are both induced in cerebral vessels, which likely provide positive signals driving the endogenous angiogenic response and vascular protection after CI.

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung.

Angara Sureshbabu et al.

Respiratory research, 16, 4-4 (2015-01-17)

Earlier studies have reported that transforming growth factor beta 1(TGFβ1) is a critical mediator of hyperoxia-induced acute lung injury (HALI) in developing lungs, leading to impaired alveolarization and a pulmonary phenotype of bronchopulmonary dysplasia (BPD). However, the mechanisms responsible for

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抗血管生成素-1抗体

from rabbit

选择尺寸

关于此项目

主要文件

属性

产品名称

biological source

conjugate

antibody form

antibody product type

clone

species reactivity

technique(s)

NCBI accession no.

UniProt accession no.

shipped in

target post-translational modification

Quality Level

Gene Information

相关类别

说明

Analysis Note

Application

Biochem/physiol Actions

General description

Immunogen

Other Notes

Physical form

安全信息

存储类别

wgk

flash_point_f

flash_point_c

文件

分析证书(COA)

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