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Merck
CN

AB10516

抗血管生成素-1抗体

from rabbit

别名:

Hepatic fibrinogen/angiopoietin-related protein, PPARG angiopoietin related protein, angiopoietin-like 4, angiopoietin-like 4 protein, angiopoietin-related protein 4, fasting-induced adipose factor, hepatic angiopoietin-related protein, peroxisome prolif

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

horse (95% sequence homology), dog (95% sequence homology), mouse (100% sequence homology), rat (95% sequence homology), bovine (95% sequence homology), mouse, human (90% sequence homology), pig (95% sequence homology)

技术

western blot: suitable

NCBI登记号

NM_001146.3

UniProt登记号

O08538

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ANGPT1(284)

相关类别

一般描述

57 kDa
哺乳动物原始脉管系统的重塑以形成成熟的心血管系统包括许多指导内皮细胞发育的因素。血管生成素-1是一种与内皮特异性Tie-2受体相互作用的血管生成分泌型蛋白。它主要在发育中的内皮细胞中表达。在胚胎发育过程中，Ang-1结合并诱导Tie-2的酪氨酸磷酸化。Ang-1似乎在介导基质和间充质中起关键作用。它介导血管成熟和稳定。Ang-1可能在心脏发育中起关键作用。Ang-1缺陷小鼠模仿Tie-2缺陷动物表现出的表型。Ang-1的同系物，称为血管生成素-2，可以作为Ang-1和Tie-2的拮抗剂。Ang-1和Ang-2具有约60%的序列同源性。

免疫原

该抗体是从用选自小鼠血管生成素-1的KLH偶联合成肽免疫的兔中产生的。

应用

抗血管生成素-1抗体是针对血管生成素-1的抗体，可用于WB。

生化/生理作用

该抗体可识别血管生成素-1。

外形

形式：纯化

分析说明

对照
小鼠肾裂解液
通过蛋白质印迹在小鼠肾裂解液中进行了评估。
蛋白质印迹分析：： 该批次的1：1,000稀释液在10 µg小鼠肾裂解液中检测到血管生成素-1。

其他说明

浓度：请参考批次特异性浓缩物的检验报告。

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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