biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITLN1(55600)
General description
30-40 kDa
A calcium-dependent lectin with affinity for furanosides, such as galactofuranosyl in bacterial arabinogalactans. 30kD of apparent molecular weight of Omentin migrate at 40-kD under reducing conditions due to glycosylation. Omentin, a novel visceral fat depot-specific secretory protein, enhance insulin-stimulated glucose transport in subcutaneous as well as omental adipocytes and may therefore be implicated in the pathogenesis of obesity.
Immunogen
Epitope: Amino acids 95-115 of Human Omentin.
Synthetic peptide: TVGDRWSSQQGSKADYPEGDG, corresponding to amino acids 95-115 of Human Omentin.
Application
Anti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB.
Western blot: 1:2,000-1:5,000 using ECL. Reacted with the ~40kDa Omentin His-tagged protein. Suggested blocking and dilution buffer is PBST with 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.
ELISA, direct and indirect: 1:2,000-1:5,000.
ELISA, direct and indirect: 1:2,000-1:5,000.
Biochem/physiol Actions
Recognizes Omentin in western blotting.
Physical form
Format: Purified
Liquid in PBS, pH7.4. Contains no preservatives.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Kseniia V Dracheva et al.
Non-coding RNA, 9(6) (2023-11-21)
Obesity is a significant risk factor for the development of type 2 diabetes mellitus (T2DM). Adipose tissue dysfunction can affect the pool of circulating exosomal miRNAs, driving concomitant disease in obesity. These exosomal miRNAs can reflect adipose tissue functionality, thus
Chi-Lam Au-Yeung et al.
Nature communications, 11(1), 3546-3546 (2020-07-17)
Advanced ovarian cancer usually spreads to the omentum. However, the omental cell-derived molecular determinants modulating its progression have not been thoroughly characterized. Here, we show that circulating ITLN1 has prognostic significance in patients with advanced ovarian cancer. Further studies demonstrate
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