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Merck
CN

AB12226

Anti-RALY Antibody

from rabbit, purified by affinity chromatography

别名:

RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)), RNA-binding protein (autoantigenic), hnRNP associated with lethal yellow protein homolog, hnRNP core protein C-like 2, RNA-binding protein (autoantigenic, hnRNP-ass

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
2
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human, rat

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... RALY(22913)

General description

RNA-binding protein RALY is a member of the RRM HNRPC family and contains a characteristic RRM (RNA recognition motif) domain. It is thought to participate in pre-mRNA splicing and may be a heterogenous nuclear ribonucleoprotein. Phosphorylation of RALY has been observed following damage to DNA. Expression has been observed in brain, heart, kidney, liver, lung, pancreas, and skeletal muscle.
~ 38 kDa observed

Immunogen

Histidine-tagged recombinant protein corresponding to human RALY.

Application

Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated RALY from HepG2 cell lysate.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
RNA Metabolism & Binding Proteins
Use Anti-RALY Antibody (rabbit polyclonal antibody) validated in WB, IP to detect RALY also known as hnRNP core protein C-like 2, RNA-binding protein (autoantigenic hnRNP-associated with lethal yellow).

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
HepG2 cell lysate
Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 1:10,000 dilution of this antibody detected RALY on 10 µg of HepG2 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Matteo Marchesini et al.
Cancer cell, 32(1), 88-100 (2017-07-04)
Amplification of 1q21 occurs in approximately 30% of de novo and 70% of relapsed multiple myeloma (MM) and is correlated with disease progression and drug resistance. Here, we provide evidence that the 1q21 amplification-driven overexpression of ILF2 in MM promotes
Emma Bondy-Chorney et al.
Cell reports, 33(4), 108318-108318 (2020-10-29)
Polyphosphates (polyPs) are long chains of inorganic phosphates linked by phosphoanhydride bonds. They are found in all kingdoms of life, playing roles in cell growth, infection, and blood coagulation. Unlike in bacteria and lower eukaryotes, the mammalian enzymes responsible for

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