Anti-NUDEL Antibody

38 kDa

NudE nuclear distribution gene E homolog (A. nidulans)-like 1 (NUDEL), also known as NDEL1, is a human gene. This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. This protein plays a role in nervous system development and is linked to LIS-1, the disease gene for a form of lissencephaly, a disorder of cortical development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synthetic Linear Peptide.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

This Anti-NUDEL Antibody is validated for use in WB for the detection of NUDEL.

Western Blot: 1:5000L

Recognizes rat NUDEL

Serum with 0.05% NaN₃

Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt.

Control
brain lysate

Routinely evaluated by immunoblot.

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