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Merck
CN

AB15794

抗-Dexras1抗体

Chemicon®, from rabbit

别名:

Activator of G-Protein Signaling 1, AGS1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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产品名称

抗-Dexras1抗体, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

rat (100% immunogen homology), human (100% immunogen homology)

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_016084.3

UniProt accession no.

Q9Y272

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... RASD1(51655)

Application

蛋白质印迹：1:1,000，小鼠脑提取物中。
最佳工作稀释度必须由最终用户进行确定。
该抗Dexras1抗体经过验证可用于WB中，以用于检测Dexras1。
研究子类别
信号神经科学
研究类别
神经科学

Biochem/physiol Actions

Dexras1（G蛋白信号传导激活剂1，AGS1）。抗体通过蛋白质印迹识别小鼠脑提取物的~33 kDa的条带。该抗体还被用于检测棕色脂肪细胞裂解液中的Dexras1。
其他物种尚未经过测试

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

Dexras1是Ras-G-蛋白超家族的成员，直接与Gialpha异源三聚体G蛋白结合，它似乎促进Gialpha上的鸟嘌呤核苷酸交换。Dexras1通过一氧化氮合酶参与NMDA受体信号传导。

Immunogen

合成肽。

Physical form

免疫亲和纯化
溶于PBS中的液体。不含防腐剂

Preparation Note

自发货之日起可在-70°C保存6个月

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Yu Zhang et al.
Aging cell, 17(3), e12754-e12754 (2018-03-27)
In neurons, increased protein-protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy-terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of Alzheimer's
Marek Lenarczyk et al.
Journal of molecular histology, 46(2), 123-136 (2014-12-24)
Activators of G-protein Signaling (AGS) are a family of accessory proteins that were discovered as modulators of heterotrimeric G-protein subunits. The primary aim of the present study was to localize Group I and II AGS proteins and determine the renal
Sudhir G Tattikota et al.
Molecular & cellular proteomics : MCP, 12(5), 1214-1225 (2013-01-30)
Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant
Li-Juan Zhu et al.
Journal of neurochemistry, 146(5), 598-612 (2018-06-03)
Anxiety disorders are associated with a high social burden worldwide. Recently, increasing evidence suggests that nuclear factor kappa B (NF-κB) has significant implications for psychiatric diseases, including anxiety and depressive disorders. However, the molecular mechanisms underlying the role of NF-κB
Sudhir G Tattikota et al.
Cell metabolism, 19(1), 122-134 (2013-12-24)
Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in

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