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Merck
CN

AB1846

Anti-C-X-C Chemokine Receptor 4 Antibody, NT

Chemicon®, from rabbit

别名:

CD184, CXCR4

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IP, WB
Citations:
25
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CXCR4(7852)

General description

40 kDa

Immunogen

Amino-terminus peptide of human CXCR4 (Berson, 1996; Leotscher, 1994).
Epitope: N-terminus

Application

Anti-C-X-C Chemokine Receptor 4 Antibody, N-terminus is an antibody against C-X-C Chemokine Receptor 4 for use in IC, IP & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Western blot: 1-2 μg/mL. HeLa cell lysates can be used as positive control. The antibody should detect a band at 40 kDa.

Immunocytochemistry: 10 μg/mL

Immunoprecipitation

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes CXCR4, N-terminus.

Physical form

Format: Purified
Protein A purified
Purified IgG in PBS containing 0.02% sodium azide.

Preparation Note

Maintain 1 year at 4°C, from date of shipment. Do not freeze. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Skin

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Xu Cui et al.
Journal of neuroscience research, 87(1), 86-95 (2008-08-20)
We tested the hypothesis that a nitric oxide donor, DETA-NONOate, up-regulates stromal cell-derived factor-1 (SDF1) and angiopoietin 1 (Ang1) in the ischemic brain and their respective receptors chemokine CXC motif receptor 4 (CXCR4) and Tie2 in the subventricular zone (SVZ)
Linhui Wang et al.
Oncology reports, 22(6), 1333-1339 (2009-11-04)
Renal cell carcinoma (RCC) shows organ-specific metastasis. This may be attributed to the fact that the CXCR4 G protein coupled receptor on RCC cells mediates chemo-attraction toward stromal-derived factor (SDF)-1 secreted by target organs. SDF-1 binding to CXCR4 initiates many
Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells.
Gu, H; Li, XU; Zhou, C; Wen, Y; Shen, Y; Zhou, L; Li, J
Oncology Letters null



全球贸易项目编号

货号GTIN
AB184604053252368936