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AB1871

抗-半胱天冬酶1抗体

Chemicon®, from rabbit

别名:

ICE

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IP, WB
Citations:
29
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable, immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NM_001223.3, NM_033292.2, NM_033293.2, NM_033294.2, NM_033295.2

UniProt accession no.

P29466

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CASP1(834)
mouse ... Casp1(12362)
rat ... Casp1(25166)

General description

半胱天冬酶-1（ICE，白介素-1b转化酶）是哺乳动物的半胱天冬酶，负责将白介素-1b和IL-18的形式蛋白水解转化为活性细胞因子。 像其他半胱天冬酶一样，半胱天冬酶-1本身被合成为一种酶，在激活过程中被裂解为大（20 kDa）和小（10 kDa）亚基。

Application

蛋白质印迹：1-4 μg/mL

免疫沉淀：4-8 μg/mL

免疫荧光：10-20 μg/mL

最佳工作稀释度必须由最终用户进行确定。
该抗半胱天冬酶-1抗体经过验证可用在IF、IP、WB中检测半胱天冬酶-1。

Biochem/physiol Actions

AB1871识别45 kDa procaspase-1和20 kDa裂解的半胱天冬酶-1。

Physical form

亲和纯化的免疫球蛋白。 在含有50%甘油、1％BSA和0.02%叠氮化钠的PBS（pH 7.2）中的溶液。

Other Notes

2024年CiteAb奖，授予在帕金森研究方面取得成功的供应商

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

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Li-Gang Zhang et al.
The Prostate, 79(12), 1439-1449 (2019-06-25)
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent disease of the urogenital system. Alcohol has been reported to be closely related to CP/CPPS. Thus, we intended to verify the role of alcohol in CP/CPPS and determine the underlying mechanism.
Zhuofan Li et al.
JCI insight, 6(7) (2021-03-11)
Vaccine delivery technologies are mainly designed to minimally invasively deliver vaccines to target tissues with little or no adjuvant effects. This study presents a prototype laser-based powder delivery (LPD) with inherent adjuvant effects for more immunogenic vaccination without incorporation of
Yan Wang et al.
The Journal of international medical research, 48(8), 300060520949767-300060520949767 (2020-09-01)
The inhibition of pyroptosis has a protective effect in sepsis-associated encephalopathy (SAE). However, the mechanisms underlying pyroptosis in SAE remain to be elucidated. Here, we investigated the effects of the caspase inhibitors, Belnacasan (Beln) and Wedelolactone (Wede), on an induced
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全球贸易项目编号

货号GTIN
AB187104053252278990