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Merck
CN

AB1921

Anti-Integrin alpha 5 (ITGA5/CD49E) Antibody

CHEMICON®, rabbit polyclonal

别名:

CD49e

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关于此项目

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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产品名称

Anti-Integrin α5 Antibody, serum, Chemicon®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ITGA5(3678)

Application

Detect Integrin α5 using this Anti-Integrin α5 Antibody validated for use in ELISA, WB, IH.
ELISA.

Western blotting: (The antigen should be separated in SDS-PAGE under reducing conditions

and does not react with non-reduced sample.): 1:5,000.

Immunohistochemistry/Immunofluorescence: 1:1,000.

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Biochem/physiol Actions

Specific for alpha5 integrin as determined by Western blotting.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Recombinant fragment of mouse alpha5 integrin (Holers et al. 1989) corresponding to amino acid residues 655-880 of the human protein (Argraves 1987). This region of the molecule is extracellular and is included in the heavy chain (120 kDa).

Physical form

Whole rabbit serum. Liquid, with 0.02% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids


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Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension.
Coyer, SR; Singh, A; Dumbauld, DW; Calderwood, DA; Craig, SW; Delamarche, E; Garcia, AJ
Journal of Cell Science null
CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes.
Nishida, T; Kawaki, H; Baxter, RM; Deyoung, RA; Takigawa, M; Lyons, KM
Journal of Cell Communication and Signaling null
Opposing effects of collagen I and vitronectin on fibronectin fibril structure and function.
Gildner, CD; Roy, DC; Farrar, CS; Hocking, DC
Matrix Biology null
Recombinant fibronectin matrix mimetics specify integrin adhesion and extracellular matrix assembly.
Roy, DC; Hocking, DC
Tissue Engineering: Part A null
Sirika Pillay et al.
Journal of virology, 91(18) (2017-07-07)
Adeno-associated virus (AAV) entry is determined by its interactions with specific surface glycans and a proteinaceous receptor(s). Adeno-associated virus receptor (AAVR) (also named KIAA0319L) is an essential cellular receptor required for the transduction of vectors derived from multiple AAV serotypes

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