20 amino acid peptide sequence within the cytoplasmic, C-terminus of mouse Flt-4

Detect FLT-4 using this Anti-FLT-4 Antibody validated for use in ELISA & WB.

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

Western blot: 1-10 μg/mL using ECL. The antibodies detected ~140 kDa band in rat liver extracts.

ELISA: 1:10,000-1:100,000, using 50-100ng of control peptide/well.

Optimal working dilutions must be determined by end user.

Recognizes mouse Flt-4 (mouse 1363-aa and human 1298-aa) a receptor protein tyrosine kinase. It is type 1 membrane protein, a receptor for VEGF-C and is expressed in adult lung, and liver, and in fetal liver, brain, intestine, and placenta. Flt-4 is also known as vascular endothelial growth factor receptor 3 (VEGFR3).

SPECIES REACTIVITIES: The peptide sequence used is relatively conserved in rat (85%) and human (73%) Flt-4/VEGFR3. No significant sequence homology is seen with VEGFR1, VEGFR2, or other tyrosine kinases. Antibody crossreactivity in other species is not established.

Liquid in PBS, containing 0.1% BSA. Affinity purified immunoglobulin.

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze and thaw.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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