AB3402P
Anti-Agouti Related Protein Antibody
Chemicon®, from rabbit
别名:
AGRP
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... AGRP(181)
General description
Agouti-related peptide-expressing (AgRP) neurons seem to be critical for the acute regulation of eating. The AgRP protein is a strong antagonis of MC3-R and MC4-R and is expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.
Immunogen
A 15 amino acid peptide near the C-terminus of mouse AGRP (Shutter et al. 1997; Ollmann et al. 1997).
Application
Detect Agouti Related Protein using this Anti-Agouti Related Protein Antibody validated for use in ELISA & WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Glucose/Glycogen Metabolism
Glucose/Glycogen Metabolism
Western blot: 1-10 μg/mL using ECL.
ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by the end user.
ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes AGRP. The immunogen shows no significant sequence homology with Agouti, tubby, tub, TULP1 or TULP2.
SPECIES REACTIVITIES: The immunogen sequence is 85% homologous with human and bovine. Reactivity with other species has not been confirmed.
SPECIES REACTIVITIES: The immunogen sequence is 85% homologous with human and bovine. Reactivity with other species has not been confirmed.
Physical form
Liquid in phosphate buffered saline containing 0.1% BSA.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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