产品名称
Anti-Defensin β3 Antibody, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... DEFB103A(414325), DEFB103B(414325)
Application
Anti-Defensin Antibody, β3 is an antibody against Defensin for use in ELISA & WB.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
Western blotting: Tricine-SDS- PAGE gels recommended: 1:500-1:1,000, migrates as a 5-6kDa band; Tricine-SDS-urea PAGE gels: Native Beta Defensin 3 migrates as a 9kDa band; the larger size is because of the reduction of the three cysteine bridges present in the peptide protein
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes the 5-6 kDa human Defensin-3, beta protein.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Beta Defensin-3 is a novel 5 kDa nonhemolytic antimicrobial protein peptide which may be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung (such as cystic fibrosis).
Immunogen
A synthetic peptide consisting of amino acids 23-33 [GIINTLQKYYC] of the human beta-defensin-3 protein.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Seiko Takeda et al.
Journal of toxicologic pathology, 26(1), 35-40 (2013-06-01)
Defensins are generally implicated in the quick resistance of epithelial surfaces to microbials; however, recent reports have indicated that defensins also have unknown purposes in relation to noninfectious diseases. In this study, the localization patterns of anti-microbial peptides, β defensins
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