产品名称
上皮钠通道β抗体, Chemicon®, from rabbit
conjugate
unconjugated
biological source
rabbit
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SCNN1B(6338)
Application
研究子类别
离子通道&转运蛋白
神经炎症&疼痛
离子通道&转运蛋白
神经炎症&疼痛
研究类别
神经科学
神经科学
蛋白质印迹:使用ECL为1-10μg/mL83-90 kDa条带,建议使用膜制备物(Masilamani et al., 1999)
ELISA:0.5-1.0 mg/mL,使用1 mg/mL对照肽包被板。
最佳工作稀释度必须由最终用户进行确定。
ELISA:0.5-1.0 mg/mL,使用1 mg/mL对照肽包被板。
最佳工作稀释度必须由最终用户进行确定。
这种上皮钠通道β抗体经验证可用于ELISA、WB检测上皮钠通道-β。
Biochem/physiol Actions
可识别大鼠上皮钠通道β(ENaC β)。免疫原与其他ENaC亚基没有明显的序列同源性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
大鼠ENaC β N端附近的20个氨基酸的肽序列。 免疫原序列在小鼠中100%保守,在兔中94%,在人中81%,在绵羊中76%,在爪蟾中64%。
Other Notes
浓度:请参考批次特异性浓缩物的检验报告。
Physical form
亲和纯化免疫球蛋白,溶于含0.1% BSA的PBS中。
Preparation Note
收到货后,在-20°C下以未稀释等分试样可保存长达6个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Xiao Sun et al.
EMBO molecular medicine, 10(10) (2018-08-30)
The shift of cytokine profile from anti- to pro-inflammatory is the most recognizable sign of labor, although the underlying mechanism remains elusive. Here, we report that the epithelial sodium channel (ENaC) is upregulated and activated in the uterus at labor
L R E Pedersen et al.
Acta physiologica (Oxford, England), 206(2), 142-149 (2012-06-12)
We wished to determine the effect of continuous β-receptor stimulation on alveolar fluid clearance and to elucidate the mechanisms behind this effect. Alveolar fluid clearance was measured in anaesthetized rats pretreated for 72 h with the β-agonist isoproterenol (200 μg kg(-1) h(-1) sc)
Takahiro Masuda et al.
American journal of physiology. Renal physiology, 315(3), F653-F664 (2018-05-24)
The chronic intrinsic diuretic and natriuretic tone of sodium-glucose cotransporter 2 (SGLT2) inhibitors is incompletely understood because their effect on body fluid volume (BFV) has not been fully evaluated and because they often increase food and fluid intake at the
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