产品名称
Anti-Organic Anion Transporting Polypeptide 1 Antibody, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLCO4A1(28231)
Application
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Research Category
Neuroscience
Neuroscience
This Anti-Organic Anion Transporting Polypeptide 1 Antibody is validated for use in ELISA, WB for the detection of Organic Anion Transporting Polypeptide 1.
Western blot: 1-10 μg/mL using ECL.
ELISA: 0.5-1 μg/mL using 1 μg/mL immunogen per well.
Optimal working dilutions must be determined by the end user.
ELISA: 0.5-1 μg/mL using 1 μg/mL immunogen per well.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes rat Organic Ion Transporter Polypetide 1 (OATP1). The immunogen shows no significant sequence homology with other OATs or other proteins
SPECIES REACTIVITIES: The immunogen sequence is unique to rat. Reactivity with other species has not been confirmed.
SPECIES REACTIVITIES: The immunogen sequence is unique to rat. Reactivity with other species has not been confirmed.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
A 17 amino acid peptide sequence near amino acid 285 of rat OATP1 (Jacquemin et al. 1994; Kullak-Ublick et al. 1995).
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Kyunghee Yang et al.
Molecular pharmaceutics, 11(3), 766-775 (2014-01-15)
Breast cancer resistance protein (BCRP) and multidrug resistance-associated protein 2 (MRP2) are members of the ATP binding cassette (ABC) transporter family located in the canalicular membrane of hepatocytes that mediate biliary excretion of many drugs and endogenous compounds. BCRP and
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