AB4326
ISL-1抗体
from rabbit, purified by affinity chromatography
别名:
ISL LIM homeobox 1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1)
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC, WB
Citations:
10
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
horse, human, mouse
species reactivity (predicted by homology)
sheep (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), equine (based on 100% sequence homology), bovine (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ISL1(3670)
General description
胰岛因子1（ISL-1）是一种转录因子，在朗格汉斯胰岛的胚胎发生中发挥重要作用。它在肾上腺髓质和背根神经节的神经元亚群、视网膜内核和神经节细胞层、松果体和大脑某些区域中表达。在小鼠胚胎中，缺乏这种基因就无法进行神经管运动神经元的分化。最近，它被确定为心脏祖细胞谱系的标志物，该谱系能够分化为所有3种主要心脏细胞类型：心肌细胞、平滑肌和内皮细胞谱系。
~39 kDa
Immunogen
KLH偶联线性肽，对应于人ISL-1。
表位：ISL-1的内部区域。
Application
ISL-1抗体是一种检测ISL-1（又称ISL LIM同源盒1、ISL1转录因子LIM/同源结构域）的兔多克隆抗体 & 已通过WB & IHC验证。
免疫组化分析：先前批次的1:300稀释液在小鼠胰腺组织中检测到ISL-1。
Biochem/physiol Actions
基于100%的序列同源性，预测会与最常见的脊椎动物物种反应。
该抗体可识别ISL-1。
Analysis Note
通过蛋白质印迹法对K562细胞裂解液进行了评估。
蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg K562细胞裂解液中检测到ISL-1。
蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg K562细胞裂解液中检测到ISL-1。
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Still not finding the right product?
试用我们的 产品选型工具 工具缩小选择范围
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Zane Zeier et al.
Experimental neurology, 271, 241-250 (2015-06-24)
A hexanucleotide repeat expansion residing within the C9ORF72 gene represents the most common known cause of amyotrophic lateral sclerosis (ALS) and places the disease among a growing family of repeat expansion disorders. The presence of RNA foci, repeat-associated translation products
Joseph A Bisson et al.
Developmental biology, 398(1), 80-96 (2014-12-09)
Wnt proteins regulate cell behavior via a canonical signaling pathway that induces β-catenin dependent transcription. It is now appreciated that Wnt/β-catenin signaling promotes the expansion of the second heart field (SHF) progenitor cells that ultimately give-rise to the majority of
Rustam Esanov et al.
Experimental neurology, 277, 171-177 (2016-01-10)
Among several genetic mutations known to cause amyotrophic lateral sclerosis (ALS), a hexanucleotide repeat expansion in the C9orf72 gene is the most common. In approximately 30% of C9orf72-ALS cases, 5-methylcytosine (5mC) levels within the C9orf72 promoter are increased, resulting in
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB4326 | 04053252278662 |