AB5320B
Anti-NG2 Chondroitin Sulfate Proteoglycan, Biotin Conjugate Antibody
from rabbit, biotin conjugate
别名:
Chondroitin sulfate proteoglycan 4, Chondroitin sulfate proteoglycan NG2, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
biotin conjugate
Clone:
polyclonal
Application:
immunocytochemistry
immunohistochemistry
immunohistochemistry
Species reactivity:
rat
Citations:
9
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
immunohistochemistry: suitable
Uniprot accession no.:
产品名称
Anti-NG2 Chondroitin Sulfate Proteoglycan, Biotin Conjugate Antibody, from rabbit, biotin conjugate
biological source
rabbit
conjugate
biotin conjugate
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), monkey (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CSPG4(1464)
mouse ... Cspg4(121021)
rat ... Cspg4(81651)
rhesus monkey ... Cspg4(713086)
Analysis Note
Control
Cryosections of rat cortex tissue
Cryosections of rat cortex tissue
Evaluated by Immunohistochemistry in cryosections of rat cortex tissue.
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected NG2 in cryosections of rat cortex tissue.
Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected NG2 in cryosections of rat cortex tissue.
Application
Anti-NG2 Chondroitin Sulfate Proteoglycan, Biotin Conjugate Antibody is an antibody against NG2 Chondroitin Sulfate Proteoglycan for use in IHC, ICC.
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected NG2 in paraffin embedded rat cortex tissue.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected NG2 in rat oligodendrocyte precursor cells. Performed without Triton.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected NG2 in rat oligodendrocyte precursor cells. Performed without Triton.
General description
NG2 is a high molecular weight, integral membrane chondroitin sulfate proteoglycan. It is found on the surfaces of an unusual class of glial cells within the developing and mature central nervous system that have the properties of oligodendrocyte precursor cells (i.e., O-2A progenitor cells). NG2 is also found on the surfaces of chondroblasts, proliferating capillary endothelial cells, some human melanoma cell lines, and on leukemic blasts in childhood acute lymphoblastic leukemia. The NG2 proteoglycan is likely to play a role in regulation of cell motility, axon outgrowth and the cellular responses to platelet-derived growth factor.
The unconjugated parent antibody (Cat. No. AB5320) has an observed molecular weight at ~270-300 kDa
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Deyu Hu et al.
Stem cell research & therapy, 15(1), 199-199 (2024-07-07)
Bone marrow-derived mesenchymal stem cell (BMMSC)-based therapy has become a major focus for treating liver fibrosis/cirrhosis. However, although these cell therapies promote the treatment of this disease, the heterogeneity of BMMSCs, which causes insufficient efficacy during clinical trials, has not
Sonja Rittchen et al.
Biomaterials, 56, 78-85 (2015-05-03)
Multiple sclerosis (MS) is a progressive demyelinating disease of the central nervous system (CNS). Many nerve axons are insulated by a myelin sheath and their demyelination not only prevents saltatory electrical signal conduction along the axons but also removes their
Meera Murgai et al.
Nature medicine, 23(10), 1176-1190 (2017-09-19)
A deeper understanding of the metastatic process is required for the development of new therapies that improve patient survival. Metastatic tumor cell growth and survival in distant organs is facilitated by the formation of a pre-metastatic niche that is composed
Alexander Balatskiy et al.
International journal of molecular sciences, 23(3) (2022-02-16)
The local development of atherosclerotic lesions may, at least partly, be associated with the specific cellular composition of atherosclerosis-prone regions. Previously, it was demonstrated that a small population of immature vascular smooth muscle cells (VSMCs) expressing both CD146 and neuron-glial
Marielle Balzano et al.
Cell reports, 26(12), 3257-3271 (2019-03-21)
In the bone marrow, CXCL12 and IL-7 are essential for B cell differentiation, whereas hematopoietic stem cell (HSC) maintenance requires SCF and CXCL12. Peri-sinusoidal stromal (PSS) cells are the main source of IL-7, but their characterization as a pro-B cell niche
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