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Merck
CN

AB5428P

Anti-Per2 Antibody

Chemicon®, from rabbit

别名:

Period Circadian Protein 2

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
western blot
Species reactivity:
mouse
Citations:
5
Technique(s):
ELISA: suitable
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-Per2 Antibody, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Per2(18627)

Application

Detect Per2 using this Anti-Per2 Antibody validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Circadian Rhythm & Sleep
Western blot: 1-10 μg/mL using ECL.

ELISA: 50-100 ng of control peptide per well.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Recognizes mouse Per 2. The immunogen shows no significant sequence homology with Per 1 or Per 3.

SPECIES REACTIVITIES: The immunogen sequence has 77% homology with rat Per2. No significant homology is seen with human Per 2 (Nagase et al. 1997). Reactivity with other species has not been confirmed.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

A 23 amino acid peptide sequence within the C-teriminus of mouse Per 2 (Albretch et al. 1997; Shearman et al. 1997; Sakamoto et al. 1998).

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA and 0.05% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Rakesh Mishra et al.
Molecular medicine (Cambridge, Mass.), 27(1), 99-99 (2021-09-08)
We have found disruption of expression of major transcriptional regulators of circadian rhythm in the kidneys of several mouse models of lupus nephritis. Here we define the consequence of this disturbance with respect to circadian gene expression and renal homeostatic
Fernando Martin Baidanoff et al.
Biomolecules, 12(7) (2022-07-28)
The molecular circadian clock is based on a transcriptional/translational feedback loop in which the stability and half-life of circadian proteins is of importance. Cysteine residues of proteins are subject to several redox reactions leading to S-thiolation and disulfide bond formation
Kyle Stokes et al.
Cellular and molecular gastroenterology and hepatology, 4(1), 95-114 (2017-06-09)
The gastrointestinal syndrome is an illness of the intestine caused by high levels of radiation. It is characterized by extensive loss of epithelial tissue integrity, which initiates a regenerative response by intestinal stem and precursor cells. The intestine has 24-hour
Xiaoqin Liu et al.
PloS one, 7(11), e50602-e50602 (2012-11-29)
Circadian rhythms in metabolism, physiology, and behavior originate from cell-autonomous circadian clocks located in many organs and structures throughout the body and that share a common molecular mechanism based on the clock genes and their protein products. In the mammalian
Peter Podobed et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(2), R121-R137 (2014-05-03)
Circadian rhythms are essential to cardiovascular health and disease. Temporal coordination of cardiac structure and function has focused primarily at the physiological and gene expression levels, but these analyses are invariably incomplete, not the least because proteins underlie many biological

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