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AB5652P

Sigma-Aldrich

Anti-Histamine Receptor 1 Antibody, CT

Chemicon®, from rabbit

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别名:
H1R
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

bovine, mouse, rat

制造商/商品名称

Chemicon®

技术

ELISA: suitable
western blot: suitable

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

mouse ... Hrh1(15465)
rat ... Hrh1(24448)

特异性

Recognizes rat Histamine Receptor 1 (HR1). The immunogen shows no significant sequence homology with other histamine receptors.

The immunogen peptide is 100% conserved in mouse and bovine, 94% in human, fish and monkey and 80% in guinea pig. Reactivity with other species has not been confirmed.

免疫原

A 17 amino acid peptide sequence near the cytoplasmic, C-terminus of rat HR1 (Fujimoto et al. 1993; Inoue et al. 1996; DeBacker et al. 1993; Fukui et al. 1994; Moguilevsky et al. 1994).
Epitope: C-terminus

应用

Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
This Anti-Histamine Receptor 1 Antibody, C-terminus is validated for use in ELISA, WB for the detection of Histamine Receptor 1.
Western blot: 1-10 μg/mL using ECL. Recognizes a 57kDa band representing the H1 receptor

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

外形

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.

储存及稳定性

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Hiroshi Azuma et al.
The Laryngoscope, 114(12), 2249-2251 (2004-11-27)
Histamine may have physiologic functions in the inner ear. The locations of histamine receptors, however, have not yet been identified in the mammalian cochlea. The aim of this study was to investigate the localization of histamine receptor subtypes (H1, H2
Matthew J Gastinger et al.
The Journal of comparative neurology, 495(6), 658-667 (2006-03-01)
Mammalian retinas are innervated by histaminergic axons that originate from perikarya in the posterior hypothalamus. To identify the targets of these retinopetal axons, we localized histamine receptors (HR) in monkey and rat retinas by light and electron microscopy. In monkeys
Kathryn M Lenz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(37), 8044-8059 (2018-08-11)
Many sex differences in brain and behavior are programmed during development by gonadal hormones, but the cellular mechanisms are incompletely understood. We found that immune-system-derived mast cells are a primary target for the masculinizing hormone estradiol and that mast cells

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