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Merck
CN

AB5848

Sigma-Aldrich

Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat

Chemicon®, from rabbit

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human, rat

制造商/商品名称

Chemicon®

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... GABBR2(9568)

一般描述

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA(A) and GABA© receptors and GABA(B), the latter of which acts through a G protein mechanism. GABA(B)R2 is one of the two G-protein coupled receptors for GABA(B) that acts as a heteromeric assembly with GABA(B)R1.

免疫原

Epitope: a.a. 42-54 rat
peptide residues 42-54 of the rat 105 kDa GABA(b)R2 protein

应用

Immunoblotting: 1:500-1:1,000. Membrane preparations with proteinase inhibitors are recommended. Whole rat brain membrane preparations. The antibody detects a ~105kDa band under standard western conditions. The immunogen used is 100% conserved in human by sequence analysis; other species have not been examined for reactivity or homology.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat is validated for use in WB for the detection of GABA B Receptor R2.

生化/生理作用

GABAB Receptor R2 subunit, N-terminus. No reactivity with GABABR1 has been detected.

外形

Format: Purified
Purified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.

制备说明

Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals.
Williams, JM; Guevremont, D; Mason-Parker, SE; Luxmanan, C; Tate, WP; Abraham, WC
The Journal of Neuroscience null
Distribution and function of GABAB receptors in spider peripheral mechanosensilla.
Panek, I; Meisner, S; Torkkeli, PH
Journal of Neurophysiology null

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