Theoretical MW is approx. 126 kDa however literature reports observed molecular weight to be 205 kDa to 220 kDa

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified

Anti-NOGO A Antibody detects level of NOGO A & has been published & validated for use in WB.

Cat. # AB5888 is specific to NOGO A. It does not recognize NOGO B or NOGO C.

Reactivity with other species has not been tested.

Routinely tested on mouse brain lysate

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