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Merck
CN

AB770

Anti-TIMP-1 Antibody

Chemicon®, from rabbit

别名:

Tissue Inhibitor of Metalloproteinase-1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
23
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

bovine, rat, ferret, sheep, horse, rabbit

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TIMP1(7076)

Immunogen

Full length purified human fibroblast tissue inhibitor of metalloproteinases {Clark, IM (1991) Matrix 11:76-85}.

Application

Anti-TIMP-1 Antibody detects level of TIMP-1 & has been published & validated for use in ELISA, WB, IH.
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs
Western Blotting at 5-10 μg/mL: recognizes a band of approximately 28-30kDa in reduced samples.

Immunohistochemistry: frozen and 4%PFA fixed paraffin sections: 5-20μg/mL enzymatic detection.



Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with TIMP1. Does not react with any other human proteins tested so far. The antibody reacts with native and denatured TIMP1 and TIMP1 in and out of enzyme/inhibitor complex.

Physical form

Purified immunoglobulin. Liquid in PBS containing 0.02% azide.

Preparation Note

Maintain refrigerated at 2-8°C for up to three months from date of receipt. For extended storage, freeze in convenient undiluted aliquots at -20°C for up to twelve months from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-1133

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

12 - Non Combustible Liquids



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Pedro Ayala et al.
American journal of physiology. Lung cellular and molecular physiology, 315(3), L390-L403 (2018-05-11)
Recurrent aspiration of gastric contents has been associated with several interstitial lung diseases. Despite this association, the pathogenic role of aspiration in these diseases has been poorly studied and little is known about extracellular matrix (ECM) changes in animal models
Muraly Puttabyatappa et al.
Reproductive sciences (Thousand Oaks, Calif.), 25(6), 882-892 (2017-03-17)
Prenatal testosterone (T)-treated sheep, similar to women with polycystic ovary syndrome (PCOS), manifests reproductive defects that include multifollicular ovarian phenotype. Women with PCOS manifest increased ovarian matrix metalloproteinases (MMPs) activity. We tested the hypothesis that gestational T excess in sheep
Pedro Ayala et al.
Respiratory research, 19(1), 57-57 (2018-04-11)
Gastric contents aspiration in humans has variable consequences depending on the volume of aspirate, ranging from subclinical pneumonitis to respiratory failure with up to 70% mortality. Several experimental approaches have been used to study this condition. In a model of



全球贸易项目编号

货号GTIN
AB77008436037124501