产品名称
抗载脂蛋白E抗体, serum, Chemicon®
biological source
goat
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
primate, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
相关类别
Application
研究类别
代谢
代谢
研究子类别
脂代谢 & 体重调节
脂代谢 & 体重调节
使用经验证可用于IH &WB的抗载脂蛋白E抗体检测载脂蛋白E。
蛋白质印迹（Schwab, 1996）：1：1,000-1：2,000
免疫组化（Summers, 1998; Wisniewski & Frangione, 1992; Schwab, 1996）
最佳工作稀释度必须由最终用户确定。
免疫组化（Summers, 1998; Wisniewski & Frangione, 1992; Schwab, 1996）
最佳工作稀释度必须由最终用户确定。
Analysis Note
对照
肝脏组织
肝脏组织
Biochem/physiol Actions
当针对合并的人血浆和两次浓缩的合并的人血清进行测试时，通过免疫电泳测定载脂蛋白E具有单特异性。通过蛋白质印迹法与载脂蛋白E亚型E2、E3和E4反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
34kda
Immunogen
重组人载脂蛋白E。
Other Notes
Physical form
未纯化
脱脂山羊抗血清，0.2 μm过滤。 Tris-盐水中的液体，pH值7.4，含0.1%叠氮化钠作为防腐剂。
Preparation Note
自发运之日起在-20°C可保存1年。等分以避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Observations in APP bitransgenic mice suggest that diffuse and compact plaques form via independent processes in Alzheimer's disease.
Lord, A; Philipson, O; Klingstedt, T; Westermark, G; Hammarstrom, P; Nilsson, KP; Nilsson, LN
The American Journal of Pathology null
The association of hepatitis C virus glycoproteins with apolipoproteins E and B early in assembly is conserved in lipoviral particles.
Boyer, A; Dumans, A; Beaumont, E; Etienne, L; Roingeard, P; Meunier, JC
The Journal of Biological Chemistry null
Jianjia Fan et al.
PloS one, 11(9), e0162384-e0162384 (2016-09-07)
The apolipoprotein E (APOE) gene is the most highly associated susceptibility locus for late onset Alzheimer's Disease (AD), and augmenting the beneficial physiological functions of apoE is a proposed therapeutic strategy. In a high throughput phenotypic screen for small molecules
Differential regulation of amyloid-? endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms.
Li, J; Kanekiyo, T; Shinohara, M; Zhang, Y; LaDu, MJ; Xu, H; Bu, G
The Journal of Biological Chemistry null
USE OF FUSED CIRCULATIONS TO INVESTIGATE THE ROLE OF APOLIPOPROTEIN E AS AMYLOID CATALYST AND PERIPHERAL SINK IN ALZHEIMER'S DISEASE.
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Technology and innovation null
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