Anti-Cholecystokinin A Receptor Antibody

FUNCTION: SwissProt: P32238 # Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
SIZE: 428 amino acids; 47841 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P32238 ## Belongs to the G-protein coupled receptor 1 family.

Synthetic peptide from the N-terminal extracellular domain of human Cholecystokinin A Receptor.

Immunohistochemistry on paraffin embedded tissue sections.

Optimal working dilutions must be determined by the end user.

Recognizes Cholecystokinin A Receptor.

Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.

Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

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