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Merck
CN

ABC148

Anti-TMEM132A Antibody

from rabbit, purified by affinity chromatography

别名:

Transmembrane protein 132A, HSPA5-binding protein 1, TMEM132A

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

Anti-TMEM132A Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, mouse

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... TMEM132A(54972)

Analysis Note

Control
Neuro2A cell lysate
Evaluated by Western Bloting in Neuro2A cell lysate.

Western Blotting Analysis: 0.1 µg/mL of this antibody detected TMEM132A in 10 µg of Neuro2A cell lysate.

Application

Detect TMEM132A using this rabbit polyclonal antibody, Anti-TMEM132A Antibody validated for use in western blotting & IHC (Paraffin).
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Neuro2A in human cerebellum and thalamus tissues.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

This antibody recognizes the cytoplasmic domain of TMEM132A.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Transmembrane protein 132A (TMEM132A), or HSPA5-binding protein 1 (HSPA5BP1), is thought to be involved in embryonic and postnatal development of the brain, and the increased cell death resistance induced by serum starvation in cultured cells. TMEM132A is known to regulate cAMP-induced GFAP gene expression through phosphorylation of STAT3.
~140 kDa observed. The calculated molecular weight of this protein is 110kDa This protein has been observed at ~135 and ~170 kDa due to glycosylation, myristoylation, and phosphorylation (Kentaro, O. H., et al. (2003). J Biol Chem. 278(12): 10531-10537.). Uncharacterized band(s) may be observed in some cell lysates.

Immunogen

Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human TMEM132A.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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