产品名称
Anti-Annexin A1, Antibody, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat, mouse
species reactivity (predicted by homology)
chimpanzee (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ANXA1(301)
Analysis Note
Control
L6 cell lysate
L6 cell lysate
Evaluated by Western Blot in L6 cell lysate.
Western Blot Analysis: 2.0 µg/mL of this antibody detected Annexin A1 in 10 µg of L6 cell lysate.
Western Blot Analysis: 2.0 µg/mL of this antibody detected Annexin A1 in 10 µg of L6 cell lysate.
Application
Anti-Annexin A1 is an antibody targeting the Annexin A1 protein, validated for use in WB & IHC.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Western Blot Analysis: 2.0 µg/mL from a representative lot detected Annexin A1 in 10 µg of C2C12, HUVEC, and NIH/3T3 cell lysate.
Immunohistochemistry Analysis: 1:500 dilution from a representative lot detected Annexin A1 in human lung tissue.
Immunohistochemistry Analysis: 1:500 dilution from a representative lot detected Annexin A1 in human lung tissue.
Biochem/physiol Actions
This antibody recognizes the C-terminus of Annexin A1
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Annexin A1 (ANXA1) is a calcium and phospholipid binding protein almost entirely restricted to microglia in the CNS. During the peripheral inflammatory response, Annexin A1 is instrumental in the phagocytosis of apoptotic leukocytes. Annexin A1 restores the ability of microglia to differentiate between apoptotic and non-apoptotic cells during inflammatory activation. Current research is geared towards using Annexin A1 as a therapeutic target in neuroinflammation. Annexin A1 has also been shown to be influential in cancer development and proliferation.
~38 kDa observed
Immunogen
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human Annexin A1.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Protein A purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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