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Merck
CN

ABC323

Sigma-Aldrich

Anti-HMMR Antibody/CD168

from rabbit, purified by affinity chromatography

别名:

Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168

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关于此项目

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

human

种属反应性(根据同源性预测)

primate (based on 100% sequence homology), monkey (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... HMMR(3161)

一般描述

Hyaluronan mediated motility receptor (HMMR) is also called Receptor for hyaluronan-mediated motility (RHAMM), Intracellular hyaluronic acid-binding protein (IHABP), and CD_antigen 168 (CD168). HMMR is involved in cell motility, and is also linked to cellular transformation and metastasis formation, regulation of extracellular-regulated kinase (ERK) activity. HMMR is expressed in breast cancer cell lines and in normal breast tissue.
~85 kDa observed

免疫原

KLH-conjugated linear peptide corresponding to the of human HMMR.

应用

Anti-HMMR Antibody/CD168 detects level of HMMR/CD168 & has been published & validated for use in HMMR/CD168.

分析说明

Evaluated by Western Blotting in MDA-MB-435 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected HMMR in 10 µg of MDA-MB-435 cell lysate.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Luke J Fulcher et al.
EMBO reports, 20(9), e47495-e47495 (2019-07-25)
The concerted action of many protein kinases helps orchestrate the error-free progression through mitosis of mammalian cells. The roles and regulation of some prominent mitotic kinases, such as cyclin-dependent kinases, are well established. However, these and other known mitotic kinases
Luke J Fulcher et al.
Science signaling, 11(531) (2018-05-24)
Members of the casein kinase 1 (CK1) family of serine-threonine protein kinases are implicated in the regulation of many cellular processes, including the cell cycle, circadian rhythms, and Wnt and Hedgehog signaling. Because these kinases exhibit constitutive activity in biochemical

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