ABC490
Anti-BCL2A1/BFL-1 Antibody
from rabbit, purified by affinity chromatography
别名:
BCL2A1/BFL-1, Bcl-2-related protein A1, Bcl-2-like protein 5, Bcl2-L-5, Hemopoietic-specific early response protein, Protein BFL-1, Protein GRS
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
1
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
bat (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), bovine (based on 100% sequence homology), Camelidae (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... BCL2A1(597)
General description
Bcl-2-related protein A1 (BCL2A1), also known as protein BFL-1, protein GRS, and Bcl-2-like protein 5 (Bcl2-L-5), is a member of the Bcl-2 family. BCL2A1/BFL-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. BCL2A1/BFL-1 expression is reported in peripheral blood, spleen, bone marrow, lung, small intestine, and testis.
~18 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to the near N-terminal of human BCL2A1/BFL-1.
Application
Anti-BCL2A1/BFL-1 Antibody is an antibody against BCL2A1/BFL-1 for use in Western Blotting and Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected BCL2A1/BFL-1 in human breast cancer and human bone marrow tissue.
Analysis Note
Evaluated by Western Blotting in human spleen tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected BCL2A1/BFL-1 in 10 µg of human spleen tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected BCL2A1/BFL-1 in 10 µg of human spleen tissue lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Warren Fiskus et al.
Blood cancer journal, 12(1), 5-5 (2022-01-13)
Treatment with Menin inhibitor (MI) disrupts the interaction between Menin and MLL1 or MLL1-fusion protein (FP), inhibits HOXA9/MEIS1, induces differentiation and loss of survival of AML harboring MLL1 re-arrangement (r) and FP, or expressing mutant (mt)-NPM1. Following MI treatment, although
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