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文件

ABD101

Sigma-Aldrich

Anti-ESRRB Antibody

from rabbit, purified by affinity chromatography

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别名:
Steroid hormone receptor ERR2, ERR beta-2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2
eCl@ss:
32160702
NACRES:
NA.75

生物来源

rabbit

质量水平

100

抗体形式

affinity isolated antibody

antibody product type

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human (based on 100% sequence homology)

technique(s)

immunocytochemistry: suitable
western blot: suitable

NCBI登记号

NP_004443

UniProt登记号

O95718

运输

wet ice

target post-translational modification

unmodified

Gene Information

human ... ESRRB(2103)

一般描述

The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.

免疫原

KLH-conjugated linear peptide corresponding to Amino acids 376-388 of Human ESRRB protein.

应用

Immunocytochemical Analysis: 1:50 dilution of this antibody detected ESRRB in a mouse embryonic stem cells.
This Anti-ESRRB Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of ESRRB.

质量

Evaluated by Western Blot in a mouse brain E16 lysate. Western Blot Analysis: 1μg/ml of this antibody detected ESRRB in a mouse brain E16 lysate. Uncharacterized bands may be observed in some cell lysates with longer exposure times.

目标描述

~56 kDa observed

其他说明

Concentration: Please refer to lot specific datasheet.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Daniela Cornacchia et al.
Cell stem cell, 25(1), 120-136 (2019-06-04)
Current challenges in capturing naive human pluripotent stem cells (hPSCs) suggest that the factors regulating human naive versus primed pluripotency remain incompletely defined. Here we demonstrate that the widely used Essential 8 minimal medium (E8) captures hPSCs at a naive-to-primed intermediate

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