ABE1026
Anti-SMARCA5 Antibody
from rabbit, purified by affinity chromatography
别名:
SMARCA5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, Sucrose nonfermenting protein 2 homolog, hSNF2H
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.43
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Species reactivity:
mouse, human
Citations:
2
Technique(s):
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-SMARCA5 Antibody, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SMARCA5(8467)
Analysis Note
Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected SMARCA5 in 10 µg of HeLa cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected SMARCA5 in 10 µg of HeLa cell lysate.
Application
Anti-SMARCA5 Antibody is an antibody against SMARCA5 for use in Western Blotting and Immunocytochemistry, Immunoprecipitation.
Immunocytochemistry Analysis: 2.0 ug/mL from a representative lot detected SMARCA5 in HeLa, A431, and NIH/3T3 cells.
Immunoprecipitation Analysis: 5.0 ug from a representative lot immunoprecipitated SMARCA5 in 500 µg of HeLa cell lysate.
Immunoprecipitation Analysis: 5.0 ug from a representative lot immunoprecipitated SMARCA5 in 500 µg of HeLa cell lysate.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Nuclear Receptors
Nuclear Receptors
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a protein encoded by the SMARCA5 gene in human. A member of the SWI/SNF family proteins with helicase and ATPase activities that are thought to regulate transcriptions by altering the chromatin structure around the target genes.
~130 kDa observed
Immunogen
Epitope: Near N-terminus
GST-tagged recombinant protein corresponding to human SMARCA5 near the N-terminus.
Other Notes
Concentration: Please refer to lot specific datasheet.
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Mark Chen et al.
Cancer research, 81(19), 4939-4948 (2021-08-14)
Chromosomal translocations generate oncogenic fusion proteins in approximately one-third of sarcomas, but how these proteins promote tumorigenesis is not well understood. Interestingly, some translocation-driven cancers exhibit dramatic clinical responses to therapy, such as radiotherapy, although the precise mechanism has not
Cuige Zhu et al.
Nature communications, 13(1), 6531-6531 (2022-11-03)
DNA replication forks are tightly controlled by a large protein network consisting of well-known core regulators and many accessory factors which remain functionally undefined. In this study, we report previously unknown nuclear functions of the actin-binding factor profilin-1 (PFN1) in
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