ABE280

Anti-Ars2 Antibody

Name: Anti-Ars2 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

别名:

Serrate RNA effector molecule homolog, Arsenite-resistance protein 2

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IP, WB

Citations:

主要文件

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse, human

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NP_001122324

UniProt accession no.

Q9BXP5

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... SRRT(51593)

General description

As a component of the nuclear RNA cap-binding complex (CBC), Ars2 is known to play a critical role in miRNA biogenesis by stabilizing and linking capped primary miRNA transcripts with the primary miRNA processing complex containing DROSHA and DGGR8. Unlike other CBC components, Ars2 expression also plays an important role in cell proliferation. In particular, depletion of Ars2 is shown to reduce the levels of several miRNAs, such as miR-21, let-7, and miR-155, which are implicated in cellular transformation.

~120 kDa observed. Uncharacterized bands at ~78 kDa and 48 kDa may be observed in some lysates.

Immunogen

Linear peptide corresponding to human Ars2.

Application

Immunoprecipitation Analysis: A representative lot from an independent laboratory detected Ars2 in IP. (Alex Achille, Department of Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA).

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Use Anti-Ars2 Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect Ars2 also known as Serrate RNA effector molecule homolog, Arsenite-resistance protein 2.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
HEK293 cell lysate

Evaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Ars2 in 10 µg of HEK293 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Anti-Ars2 Antibody

from rabbit, purified by affinity chromatography

选择尺寸

关于此项目

主要文件

属性

biological source

conjugate

antibody form

antibody product type

clone

purified by

species reactivity

technique(s)

NCBI accession no.

UniProt accession no.

shipped in

target post-translational modification

Quality Level

Gene Information

说明

General description

Immunogen

Application

Physical form

Preparation Note

Analysis Note

Other Notes

Disclaimer

安全信息

存储类别

wgk

flash_point_f

flash_point_c

文件

分析证书(COA)

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