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Merck
CN

ABE480

Anti-Centrin-2 Antibody

serum, from rabbit

别名:

Centrin-2, Caltractin isoform 1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC, IP, WB
Citations:
2
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse, rat

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CETN2(1069)

General description

Centrin-2 is also called Caltractin isoform 1. Centrin-2 is involved in microtubule organization, structure and function, and is required for centriole duplication and spindle formation. Centrin-2 also has a role in regulating cytokinesis, genome stability and global genome nucleotide excision repair (GG-NER) as component of the XPC complex.
~18 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

Immunogen

Recombinant protein corresponding to human Centrin-2.

Application

Anti-Centrin-2 Antibody is a highly specific rabbit polyclonal antibody, that targets Centrin & has been tested in western blotting, ICC, IHC & IP.
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in MDCK cells (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in wild type and galectin-3 null mouse kidney tissues (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Centrin-2 in MDCK cell lysate (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Analysis Note

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Centrin-2 in 10 µg of Jurkat cell lysate.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Renee A Lopez et al.
Bio-protocol, 7(21), e2599-e2599 (2017-11-05)
Male gametes (spermatozoids) are the only motile cells produced during the life cycle of land plants. While absent from flowering and most cone-bearing plants, motile cells are found in less derived taxa, including bryophytes (mosses, liverworts and hornworts), pteridophytes (lycophytes
Ting Zhang et al.
Nature communications, 13(1), 6907-6907 (2022-11-15)
Transcription replication collisions (TRCs) constitute a major intrinsic source of genome instability but conclusive evidence for a causal role of TRCs in tumor initiation is missing. We discover that lack of the H4K20-dimethyltransferase KMT5B (also known as SUV4-20H1) in muscle



全球贸易项目编号

货号GTIN
ABE48004053252913938