ABN192
抗-ZFP36L1抗体
from rabbit, purified by affinity chromatography
别名:
Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human
Citations:
2
Technique(s):
western blot: suitable
Uniprot accession no.:
产品名称
抗-ZFP36L1抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
bovine (based on 100% sequence homology), canine (based on 100% sequence homology), horse (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ZFP36L1(677)
Application
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
抗-ZFP36L1可检测ZFP36L1蛋白的水平&已发表&已验证可用于WB。
Biochem/physiol Actions
该抗体识别ZFP36L1的C末端。
Analysis Note
对照
HeLa细胞裂解液
HeLa细胞裂解液
通过 HeLa 细胞裂解液中的蛋白质印迹进行了评估。
蛋白质印迹分析：1 µg/ml该抗体可在10 µg HeLa细胞裂解液中检测到ZFP36L1。
蛋白质印迹分析：1 µg/ml该抗体可在10 µg HeLa细胞裂解液中检测到ZFP36L1。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
作为锌指蛋白ZFP36/tristetraprolin（TTP）家族的成员，ZFP36L1充当RNA结合蛋白（RBP），已知其与mRNA的3’个非翻译区中富含AU的元件相互作用，从而导致其降解。它作为角质形成细胞衍生的生长因子和细胞因子的靶标。据报告，ZFP36L1在各种生理过程中起重要作用，包括伤口愈合，表皮稳态，炎症，红系分化，胸腺细胞发育以及防止恶性转化。ZFPP36L1基因的缺陷与多发性硬化和癌症有关。
观察值〜38 kDa
Immunogen
KLH 偶联的线性肽，对应于人ZFP36L1的C末端。
表位：C端
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
Preparation Note
自收到之日起，在 2-8°C 条件下可稳定保存1年
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Ming-Tai Chen et al.
Scientific reports, 5, 16229-16229 (2015-11-07)
RNA binding proteins (RBPs)-mediated post-transcriptional control has been implicated in influencing various aspects of RNA metabolism and playing important roles in mammalian development and pathological diseases. However, the functions of specific RBPs and the molecular mechanisms through which they act
Branka Popović et al.
Cell reports, 42(5), 112419-112419 (2023-04-19)
Potent T cell responses against infections and malignancies require a rapid yet tightly regulated production of toxic effector molecules. Their production level is defined by post-transcriptional events at 3' untranslated regions (3' UTRs). RNA binding proteins (RBPs) are key regulators in
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