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Merck
CN

ABN38

Anti-RAB35 Antibody

from rabbit, purified by affinity chromatography

别名:

Ras-related protein Rab-35, GTP-binding protein RAY, Ras-related protein Rab-1C

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
1
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, human, horse

species reactivity (predicted by homology)

canine (based on 100% sequence homology), equine (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable (paraffin), western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... RAB35(11021)

General description

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.
~19 kDa observed. The calculated molecular weight is 23 kDa

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.
This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

Biochem/physiol Actions

This antibody recognizes RAB35 at the C-terminus.

Analysis Note

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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S Daniel et al.
Cell death discovery, 4, 7-7 (2018-08-01)
Glaucoma is a neurodegenerative disease with retinal ganglion cell (RGC) loss, optic nerve degeneration and subsequent vision loss. There are about 30 different subtypes of RGCs whose response to glaucomatous injury is not well characterized. The purpose of this study



全球贸易项目编号

货号GTIN
ABN3804053252423703