ABN44
抗FGF10抗体
from rabbit, purified by affinity chromatography
别名:
Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
13
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
species reactivity (predicted by homology)
rhesus macaque (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable (paraffin), western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FGF10(2255)
General description
可观察到约23 kDa的条带
成纤维细胞生长因子10（FGF10）是成纤维细胞生长因子家族的一员，在细胞分化、组织修复、肿瘤生长、胚胎发育和细胞增殖等方面发挥着重要的调控作用。 FGF10突变与泪道-耳道-牙指综合征(LADDS)相关，LADDS是外胚层发育不良的一种形式。
Immunogen
对应于人FGF10的KLH偶联肽。
Application
使用经过验证可用于WB、IH（P）的抗FGF10抗体检测FGF10。
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
蛋白质印迹分析：0.5 µg/mL的代表性批次在10 µg小鼠脑组织裂解物中检测到FGF10。
免疫组织化学分析：代表性批次的1:1,000稀释液在小鼠上皮细胞、小鼠肝脏、人大脑和人小脑组织中检测到FGF10。
免疫组织化学分析：代表性批次的1:1,000稀释液在小鼠上皮细胞、小鼠肝脏、人大脑和人小脑组织中检测到FGF10。
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
Preparation Note
自收到之日起，在2-8°C条件下可稳定保存1年。
Analysis Note
对照
A549细胞裂解液
A549细胞裂解液
已通过蛋白质印迹对A549细胞裂解液进行了评估。
蛋白质印迹分析：0.5 µg/mL该抗体可在10 µg的A549细胞裂解液中检测到FGF10。
蛋白质印迹分析：0.5 µg/mL该抗体可在10 µg的A549细胞裂解液中检测到FGF10。
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Shawn Liang et al.
Development (Cambridge, England), 145(2) (2018-01-24)
The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ
Nan Wang et al.
Cell proliferation, 55(11), e13315-e13315 (2022-07-20)
Ultraviolet light B (UVB) irradiation can induce skin injury and result in keratinocytes proliferation inhibition. However, the molecular understanding of the repair during UVB-induced cell proliferation inhibition remains poorly understood. The purpose of this study was to explore the role
Thomas Volckaert et al.
Developmental cell, 43(1), 48-59 (2017-10-11)
The lung harbors its basal stem/progenitor cells (BSCs) in the protected environment of the cartilaginous airways. After major lung injuries, BSCs are activated and recruited to sites of injury. Here, we show that during homeostasis, BSCs in cartilaginous airways maintain
Grinu Mathew et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(46), 13156-13161 (2016-11-02)
Deficiency in PTEN (phosphatase and tensin homolog deleted on chromosome 10) is the underlying cause of PTEN hamartoma tumor syndrome and a wide variety of human cancers. In skin epidermis, we have previously identified an autocrine FGF signaling induced by
Roberta Haddad-Tóvolli et al.
American journal of physiology. Endocrinology and metabolism, 324(2), E154-E166 (2023-01-05)
Maternal obesity is an important risk factor for obesity, cardiovascular, and metabolic diseases in the offspring. Studies have shown that it leads to hypothalamic inflammation in the progeny, affecting the function of neurons regulating food intake and energy expenditure. In
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