Anti-PDE4B2 Antibody

Phosphodiesterase 4B2 (PDE4B2) is a member of the PDE cyclic nucleotides. PDE4B2 is thought to contain both UCR1 and UCR2 regulatory units. PDE4B2 has been associated with schizophrenia and depression and could be a promising target for autism therapies.

This antibody recognizes PDE4B2 at the N-terminus.

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of human PDE4B2.

Anti-PDE4B2 Antibody is an antibody against PDE4B2 for use in WB.

Research Category
Signaling

Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

Evaluated by Western Blot in Rat brain membrane tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected PDE4B2 on 10 µg of Rat brain membrane tissue lysate.

~78 kDa observed. UniProt describes 3 isoforms produced by alternative splicing: Isoform PDE4B1 at 83.3 kDa, Isoform PDE4B2 at 64.5 kDa, and Isoform PDE4B3 at 82.1 kDa

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Rat brain membrane tissue lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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