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Merck
CN

ABS463

Anti-TET3 Antibody

from rabbit, purified by affinity chromatography

别名:

Ten-eleven-translocation family 3

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

Anti-TET3 Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... TET3(200424)

Analysis Note

Control
SK-N-SH cell lysate
Evaluated by Western Blotting/Peptide Inhibition Assay in SK-N-SH cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected TET3 in 15 µg of SK-N-SH cell lysate.

Application

Anti-TET3 Antibody is a highly specific rabbit polyclonal antibody, that targets Methylcytosine dioxygenase TET3 & has been tested in western blotting.
Research Category
Signaling
Research Sub Category
Developmental Signaling

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Methylcytosine dioxygenase TET3 (TET3) is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET3 is involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization. TET3 is expressed in colon, muscle, adrenal gland, and peripheral blood lymphocytes. It is also expressed in fetal brain but not adult brain.
~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 3 isoforms at ~77 kDa, ~167 kDa, and ~180 kDa

Immunogen

KLH-conjugated linear peptide corresponding to human TET3.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Aixia Liu et al.
iScience, 24(9), 103065-103065 (2021-09-28)
A conceptual framework for understanding abnormal endometrial decidualization, with considerable significance for the diagnosis and treatment of abnormal decidualization-related changes in non-receptive endometrium in implantation failure during early pregnancy is very important. Here, we found the expression levels of miR-29a
An-Ping Lin et al.
Leukemia, 36(4), 1150-1159 (2022-01-09)
Mitochondria can function as signaling organelles, and part of this output leads to epigenetic remodeling. The full extent of this far-reaching interplay remains undefined. Here, we show that MYC transcriptionally activates IDH2 and increases alpha-ketoglutarate (αKG) levels. This regulatory step
ZhiJun Qiu et al.
Cell chemical biology, 27(5), 538-550 (2020-02-27)
Mitochondrial D2HGDH and L2HGDH catalyze the oxidation of D-2-HG and L-2-HG, respectively, into αKG. This contributes to cellular homeostasis in part by modulating the activity of αKG-dependent dioxygenases. Signals that control the expression/activity of D2HGDH/L2HGDH are presumed to broadly influence

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